Big B Files Stand 1

OK Folks....the 2021 NCAA Men's March Madness Tournament is underway. Below is a trivia question regarding the tournament, especially in the way of major upsets and please answer the poll question WITHOUT DOING ANY research (online or offline).  Here is the trivia question:

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True or False.....A 16 seed has never beaten a 1 seed in the opening round of the NCAA March Madness Tournament?
True or False.....A 16 seed has never beaten a 1 seed in the opening round of the NCAA March Madness Tournament?
True or False.....A 16 seed has never beaten a 1 seed in the opening round of the NCAA March Madness Tournament?

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